5-MeO-DMT is the current psychedelic de jour, celebrated by medical science hungry for a short-lasting chemical to help relieve the mental turmoil of the ego, and by spiritual enthusiasts eager to reveal the Divine within in ceremonial and psychonautical contexts.

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In the beginning of the DMT: The Spirit Molecule documentary Rick Strassman MD says modestly: “DMT is a compound in the brain that can elicit the mystical experience.”

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Over the years, my work with psychedelics has focused on what is genuinely happening, not just in terms of what these substances are doing to our brain chemistry, or their medicalization, but their profound spiritual components.

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The Bufo Alvarius toad, also known as the Colorado River toad or Sonoran Desert toad, is native to the southwestern United States and northern Mexico, and secretes a substance from its paratoid glands containing 5-MeO-DMT, a potent psychedelic compound that has fascinated researchers, spiritual seekers, and the indigenous cultures of Sonora alike.

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I think a lot of the commentators around this issue default to very simplistic positions and there’s a lot more room for nuance. You know, it’s not as easy to say that organic or synthetic 5-MeO-DMT is better than the other.

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A curious thing, this hostel full of “Heads”, to use the 60s vernacular. Drug-taking explorers of the innerspaces, well-versed psychonauts who have broken open their heads and had a good look around the infinite spaces found there.

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